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BaNG Nematode and Neglected Genomics |
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| The Blaxter Lab at the Institute of Evolutionary Biology, University of Edinburgh | ||
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Nematode and Neglected Genomics at www.nematodes.org
The Blaxter lab website, databases and services, version 3.0
NEWS:
JULY 2009: The GenePool starts work on a £2.5 million upgrade funded by the MRC to deliver higher throughput and new genomics technologies to users: see the GenePool website for information.
JULY 2009: Defining one of the fundamental numbers in evolution.
In collaboration with the lab of Prof. Peter Keightley, we have been working on the estimation of the rate of mutation accumulation in inbred lines of Drosophila melanogaster. Natural selection acts on standing genetic variation between organisms, and mutation is one of the key processes generating variation. Using Illumina SOLEXA next genertaion sequencing, the complete genomes of three D. melanogaster 'mutation accumulation lines' were sequenced, and the (very few) novel mutations identified. The answer? ~3 x 10e-9 per base per generation. See the GenePool NEWS pages for more information.
Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines
Peter D. Keightley, Urmi Trivedi, Marian Thomson, Fiona Oliver, Sujai Kumar, and Mark L. Blaxter
Genome Res. 2009;19 1195-1201http://www.genome.org/cgi/doi/10.1101/gr.091231.109
Contact Peter Keightley at Keightley.genomeres2009@gmail.com
NEMBASE4 released
NEMBASE4, our Nematode EST Analysis Resource, is now live.
NEMBASE4 includes robust protein predictions (NemPep4), and protein families (NemFam3) for 63 species and over 250,000 proteins.NEMBASE4 was built by Ben Elsworth with assistance from James Wasmuth and Mark Blaxter
This website offers links to
serving genomics information for nematodes and other metazoan phyla freely downloadable solutions to expressed sequence tag analysis problems, DNA barcode analysis and phylogenomics the work we do in IEB, Edinburgh on the evolution and diversity of animals our services
The GenePool sequencing service and the NERC MGF sequencing facility Please use the navigation bar on the right to tour this site.
The website is continuously "under reconstruction" - please email mark.blaxter-at-ed.ac.uk if you find a significant broken link.
BaNG website, version 3.02, August 1st 2008
...other interesting things... 
The human scabies mite Sarcoptes scabei. See the ARTHROPODA database for analyses of ESTs from this chelicerate and many other arthropods. |