BaNG - Blaxter Nematode and Neglected Genomics
  The C. elegans genome
     Introduction to the genome of a model nematode
       Mark Blaxter at the Institute of Evolutionary Biology, University of Edinburgh
How was the genome sequenced?
Annotating the genome
 


Genes in the C. elegans genome

(based on the 1998 Science paper)

Protein-coding Genes | RNA Genes

gene type

numbers

comment

protein-coding genes

19,099

protein-coding genes with a significant peptide similarity to non-nematode proteins

42%

60% of these have EST matches

protein-coding genes with a significant peptide similarity nematode proteins

34%

20% of these have EST matches

protein-coding genes with no significant peptide similarity any proteins

24%

gene type

number

comment

RNA-coding genes *

tRNAs

877

44% of these are on the X chromosome, which is only 20% of the total sequence

[tRNA pseudogenes]

198

snRNAs

72

U1

14

U2

21

U4

5

U5

12

U6

20

17 of these are 100% identical

srpRNAs

5

SSU, 5.8S and LSU rRNA tandem repeat

60 copies

chromosome I

5S rRNA - SL1 RNA tandem repeat

>100 copies

chromosome V

SL2 RNA genes

~20

distributed

* Note that there are many new RNA genes, particularly the noncoding microRNAs involved in RNA silencing.

These pages were written by Mark Blaxter and last updated in early 2007.
Contact the www.nematodes.org webmaster if there are problems.