C. elegans growth factor genes and their receptors after Ruvkun and Hobert, Science December 11, 1998 TGF beta pathway TGF beta ligands 4 TGF beta receptors 3 Smad adaptor proteins 6 Wingless/Wnt pathway Wnt-like ligands 5 Frizzled-like receptors 4 Components of the signal transduction pathway 11 lin-12/Notch/EGF signalling pathway lag-2 type ligands 4 lin-12 type ligands 2 Components of the signal transduction pathway 11 Receptor tyrosine signalling pathway Receptors 28 Components of the signal transduction pathway 21 Cytoplasmic tyrosine kinases 22 (Src, Abl, Fak and 19 Fes/Fer) Toll signalling pathway components 1 (there is no orthologue of the Toll receptor) Hedgehog signalling pathway components 4 (there is no HH ligand)
C. elegans growth factor genes and their receptors
after Ruvkun and Hobert, Science December 11, 1998
TGF beta pathway
TGF beta ligands
4
TGF beta receptors
3
Smad adaptor proteins
6
Wingless/Wnt pathway
Wnt-like ligands
5
Frizzled-like receptors
Components of the signal transduction pathway
11
lin-12/Notch/EGF signalling pathway
lag-2 type ligands
lin-12 type ligands
2
Receptor tyrosine signalling pathway
Receptors
28
21
Cytoplasmic tyrosine kinases
22 (Src, Abl, Fak and 19 Fes/Fer)
Toll signalling pathway components
1 (there is no orthologue of the Toll receptor)
Hedgehog signalling pathway components
4 (there is no HH ligand)