Dr Dominik Rückerl
Location: Room 304, Ashworth Laboratories
Phone: 0131 650 7317
Email: dominik.ruckerl@ed.ac.uk
Website: http://www.nematodes.org/allenlab/people/ruckerl.htm
CV
- 2007-current: Postdoctoral Fellow in the Allen Lab, Institute of Immunology and Infection Research (3IR), University of Edinburgh: “Role of alternatively activated macrophages during helminth infections”
- 2004-2007: PhD- Junior Research Group Molecular Infection Biology, Research Center Borstel affiliated with the University of Lubeck, Germany
- 1997-2003: Diplom-Ingenieur (equivalent MSc.) in medical Biotechnology, Technical University of Berlin, Germany
Publications
- Jenkins SJ, Rückerl D, Cook PC, Jones LH, Finkelman FD, van Rooijen N, MacDonald AS and Allen JE.
- Local macrophage proliferation, rather than recruitment from the blood, is a signature of Th2 inflammation. Science. Published on-line May 12. Supplementary on-line material.
- Whyte CS, Bishop ET, Rückerl D, Gaspar-Pereira S, Barker RN, Allen JE, Rees AJ, Wilson HM.
- Suppressor of Cytokine Signaling (SOCS)1 is a key determinant of differential macrophage activation and function. Journal of Leukocyte Biology. May 31. [Epub ahead of print].
- Nigg AP, Zahn S, Rückerl D, Holscher C, Yoshimoto T, Ehrchen JM, Wolbing F, Udey MC, von Stebut E.
- Dendritic cell-derived IL-12p40 homodimer contributes to susceptibility in cutaneous leishmaniasis in BALB/c mice. J. Immunol 2007 Jun 1;178(11):7251-8.
- Hopner S, Dickhaut K, Hofstatter M, Kramer H, Rückerl D, Soderhall JA, Gupta S, Marin-Esteban V, Kuhne R, Freund C, Jung G, Falk K, Rotzschke O.
- Small organic compounds enhance antigen loading of class II major histocompatibility comples proteins by targeting the polymorphic P1 pocket. J Biol Chem. 2006 Dec 15;281(50):38535-42.
- Rückerl D, Hessmann M, Yoshimoto T, Ehlers S, Holscher C.
- Alternatively activated macrophages express the IL-27 receptor alpha chain WSX-1. Immunobiology. 2006 Jul;211(6-8):427-36.
- Holscher C, Holscher A, Rückerl D, Yoshimoto T, Yoshida H, Mak T, Saris C, Ehlers S.
- The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis. J Immunol. 2005 Mar 15;174(6):3534-44.
- Zeisig R, Rückerl D, Fichtner I.
- Reduction of tamoxifen resistance in human breast carcinomas by tomoxifen-containing liposomes in vivo. Anticancer Drugs . 2004 Aug;15(7):707-14.