Release 1: 1st Nov 1997 Please note: the table is still incomplete: we are working to add gene names and identifiers to it. Please do contact us if something (ie your favourite gene) is missing!

This table lists the currently accepted gene names (three-letter designations) for genes from filarial nematodes. This naming scheme was described in Parasitology Today (Nov 1997), and is based directly on those developed for Caenorhabditis elegans [Horvitz, H.R., et al. (1979) A uniform genetic nomenclature for the nematode Caenorhabditis elegans. Mol. Gen. Genet. 175, 129-133] and plant parasitic nematodes [Bird, D.M. and D.L. Riddle (1994) A genetic nomenclature for parasitic nematodes. J. Nematol. 26, 138-143]. We encourage all filarial researchers to use these designations, to reduce confusion and complexity. If you would like to propose a new gene name, or be allocated a new number form an existing named gene set, please contact FUNK by email or phone (Mark Blaxter, phone +44 131 650 6760, email: mark.blaxter@ed.ac.uk).

We are working hard on the production of a public release of a non-redundant gene sequence dataset from the over 11,000 ESTs generated by the Brugia Genome Project, and the thousands available for Onchocerca volvulus. These "CLUSTERS" will allow researchers to uniquely refer to all ESTs which derive from a single gene, and should reduce confusion in reporting of experimental results (see Parasitology Today article for rationale).

The gene names are linked to listings of the current gene name-number combinations allocated. The Nomenklature Kontroller is the person or group who will hand out numbers in order: you should contact them (or FUNK directly) if you wish to add genes to the set.

Gene name	Description	Nomeklature Kontroller	Comments
act	actin	FUNK
alt	abundant larval transcript	B. Gregory
cdd	cytidine deaminase	B. Gregory
chi	chitinase	FUNK
col	collagen	FUNK	complex gene family: naming is not complete
cpl	cysteine protease, cathepsin L like	FUNK
cpi	cysteine protease inhibitor (cystatin)	B. Gregory
efa	elongation factor 1 - alpha	FUNK
gpx	glutathione peroxidase	FUNK	major surface antigen of adult filaria
gst	glutathione-S-transferase	FUNK
her	homologue of C. elegans her gene	I. Kamal
lsu	large subunit ribosomal RNA	M. Blaxter	also known as 28S RNA
mitochondrial genes	the twelve protein-coding and 2 rRNA genes of the mt genome	H. Helmy and M. Blaxter	cox, ndh, atp genes
muc	mucin	M. Blaxter
nhr	nuclear hormone receptor	Claude Maina, NEB	gene ID/names will be posted soon
rbp	RNA binding protein	B. Gregory
rpl	large ribosomal subunit protein	M. Blaxter
rpo	other ribosomal protein	M. Blaxter
rps	small ribosomal subunit protein	M. Blaxter
shp	microfilarial sheath protein
slt	small larval transcript	B. Gregory
spn	serpin	A. Scott	serine protease inhibitor
ssu	small subunit ribosomal RNA gene	M. Blaxter	also known as 18S RNA
sxc	six-cysteine repeat motif gene	M. Blaxter	the repeat is also known as NC6#1
tmy	tropomyosin	Ted Bianco
tph	tumour protein homologue	B. Gregory
tpx	thioredoxin peroxidase	A. Scott
tua	alpha tubulin	FUNK
tub	beta tubulin	FUNK
tyr	tyrosinase	M. Blaxter