BaNG - Blaxter Nematode and Neglected Genomics
  BaNG
  Nematode and Neglected Genomics
University of Edinburgh
      The Blaxter Lab at the Institute of Evolutionary Biology, University of Edinburgh
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The Filarial Genome Project

The Filarial Genome Project (FGP) is a multinational initiative to
* identify new drug targets in human parasitic filarial nematodes through EST sequencing
* identify new vaccine candidates in human parasitic filarial nematodes through EST sequencing
* map and sequence the genome of the filariasis nematode Brugia malayi
General Information

* Filarial Biology and Pathology * The Filarial Genome Project *

Genome Information

* Brugia EST sequencing * Other filarial ESTs *

* Brugia malayi Genome Sequencing at TIGR *

* Brugia malayi genome sequence from Edinburgh/Sanger Institute *

* Wolbachia genome sequencing of Brugia and Onchocerca *


see below for more details....

what

why

who/curator

FilGenNet

The FGP www site including summaries of findings, methods, resources and contacts

Mark Blaxter

Filarial Biology and Pathology

An introduction to the biology of filaria and the diseases they cause

Mark Blaxter

Filarial nematode EST datasets

The NEMBASE database includes EST information on several filarial nematodes. NEMBASE is a postgreSQL based database for the display and analysis of "fragmented" or "partial" genome sequence, such as that produced in EST or GSS projects

Mark Blaxter

Filarial gene Nomenclature

We host the FUNK gene nomenclature database for B. malayi

Mark Blaxter

Brugia malayi Genome mapping

Using gridded BAC libraries, we are generating genome maps for Brugia malayi

Mark Blaxter

Brugia malayi Genome Sequencing at TIGR

TIGR has been funded by the US NIAID to perform an eight-fold coverage shotgun sequence survey of the Brugia malayi genome.

For B. malayi Comments/Questions send mail to bmalayi@tigr.org

Brugia malayi Genome Survey Sequencing (GSS)

In collaboration with the Sanger Institute we are generating GSS data for B. malayi

Claire Whitton and Mark Blaxter

Brugia malayi genome sequence from Edinburgh and the Sanger Institute

In collaboration with the Sanger Institute we are sequncing selected B. malayi BAC clones that cover genes-of-interest.

Mark Blaxter

The Brugia malayi mitochondrial genome

We have sequenced the 13 kb mitochondrial genome of B. malayi

Mark Blaxter

The Wolbachia endosymbionts of Brugia malayi and Onchocerca volvulus

Filarial nematodes live in symbiosis with a bacterial partner, closely related to the Wolbachia parasites of arthropods. We are in collaboration with the Sanger Institute, NEB and TIGR, sequencing and analysing the genomes of two nematode symbionts

Katelyn Fenn and Mark Blaxter

...other interesting things...


Trichinella spiralis
The parasitic nematode Trichinella spiralis.
T. spiralis causes trichinosis in humans (and is the reason why we must cook pork and wild game well before eating). Its first stage larvae live INSIDE muscle cells. See NEMBASE3 for analyses of ESTs from this parasite and many other nematodes.
the content of these pages is copyright Mark Blaxter and colleagues. Contact the webmaster if there are problems.