Clade V

Clade V includes both freeliving and parasitic nematodes. The Strongylida are vertenrate parasites, while the Diplogasterida and Rhabditida are (mostly) freeliving bacteriovores.

Strongylida

database

description

EST effort

Haemonchus contortus

NEMBASE

Haemonchus contortus is also known as the barber's pole worm of sheep. It is a blood feeding nematode, and is a major pathogen of sheep flocks worldwide.

ESTs are being sequenced in Edinburgh in collaboration with David Knox (Moredun Institute; libraries), Doug Jasmer (WA, USA; libraries) and the Pathogen Sequencing Unit at the Sanger Institute.

Teladorsagia circumcincta

NEMBASE

T. circumcincta (also previously called Ostertagia circumcincta) is a parasite of sheep of economic importance to UK agriculture.

ESTs are being sequenced in Edinburgh in collaboration with David Knox (Moredun Institute; libraries), and the Pathogen Sequencing Unit at the Sanger Institute.

Necator americanus

NEMBASE

an analysis of the first set of ESTs published is available here

Necator americanus is one of the human hookworms, which infect an estimated one billion prople worldwide. It is a blood-feeder and is responsible for significant morbidity due to anaemia, and infection can be lethal.

ESTs are being sequenced in Edinburgh in collaboration with David Pritchard (Nottingham; libraries), and the Pathogen Sequencing Unit at the Sanger Institute.

Nippostrongylus brasiliensis

NEMBASE

N. brasiliensis is a rodent parasite that is used as a model for the study of the immune resonses to infection.

ESTs are being analysed in Edinburgh in collaboration with Rick Maizels (Edinburgh).

Ancylostoma caninum

http://www.nematode.net/

A. caninum is a dog hookworm, closely related to the human hookworm, A. duodenale

ESTs are being sequenced in Washington university St Louis.

Ancylostoma duodenale

http://www.nematode.net/

A. duodenale is one of the human hookworms, which infect an estimated one billion prople worldwide. It is a blood-feeder and is responsible for significant morbidity due to anaemia, and infection can be lethal.

ESTs are being sequenced in Washington university St Louis.

Rhabditina

Caenorhabditis elegans

WORMBASE

C. elegans is a freeliving bacteriovore. The complete genome has been sequenced.

140,000 ESTs have been sequenced, primarily by Yuji Kohara's group in NIG, Japan. See the C. elegans Genome pages.

Diplogasterida

Pristionchus pacificus

http://www.nematode.net/

P. pacificus is a freeliving bacteriovore, developed as a sattelite genetic model to C. elegans.

ESTs are being sequenced in Washington University St Louis.

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